The advancement of the development of the humanities, as one of the urgent requirements, needs some arrangements. One of these requirements is to reach a collective agreement to accept the ontological propositions on the human sciences production process. Since the positivist paradigm in the last two centuries has actually had a more influential paradigm in universities, the study of its shortcomings from the perspective of Islamic ontology is the subject of this research. The research method is qualitative method which has been carried out with a deductive attitude to the existing sources of two paradigms. To this end, positivist propositions were raised and criticized on issues of "unity and plurality", "endlessness of the being," the cause-effect system, the "material and transcendental world", and "the position of a perfect human being in the universe". The results showed that the acceptance of different ontological propositions leads to the production of different types of knowledge, although there may be some similarities. Hence, the establishment of the Islamic Humanities systematics for the production of knowledge is in accordance with the new needs of the community, and for a common humanities audit.